Research at the Carmel Lab

We are a purely computational research group exploring a wide range of topics in molecular evolution and genetics. Our primary focus lies in human evolution and history, with a particular interest in leveraging ancient DNA to uncover genetic and epigenetic changes that shaped us as a species.

Paleoepigenetics

The Carmel Lab develops techniques to reconstruct premortem DNA methylation maps from ancient genomes and uses them to study evolutionary changes in gene regulation, ancient environments, and phenotypic adaptations.

Paleoepigenetics

Paleogenetics

The Carmel Lab leverages the sequencing of ancient genomes to uncover the molecular history and demographic events that have shaped populations worldwide, with a particular focus on the Levant.

Paleoepigenetics

Tools

The Carmel Lab develops a diverse array of computational tools designed to address challenges in areas such as enrichment testing, data visualization, and ancient DNA analysis pipelines.

Paleoepigenetics

RNA biology

The Carmel Lab studyies many aspects of RNA biology, including splicing, nonsense-mediated decay, 3'-end processing, circular RNAs, microRNAs and more recently tRNA-fragments.

Paleoepigenetics