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Award Liran won the Michael Milken prize for continous excellence in teaching.


Conference Liran gave a keynote lecture at annual meeting of the Israel Society of Skeletal Biology and Medicine (ISSBM), held at Tel Aviv University. Liran talked about the evolution of the moden human voice box anatomy.

Conference Liran and Lily both gave talks at the 1st Israeli Population Genetics Meeting, held at MyHeritage offices in Israel. Lily talked about the genetics of the Levant Bronze and Iron Age populations, and Liran talked about the anatomical reconstruction of the Denisovans.

Conference Liran gave a talk at the 5th Darwin Day Symposium, titled "Homo Loquens: Interdisciplinary Perspectives on the Evolution of Language", held at the University of Haifa, Israel. Liran talked about the anatomical changes in the voice box of modern humans.

welcomeWe welcome Manuel Ferrando-Bernal to the lab. Manuel is a PhD student in Barcelona, in the group of Prof. Carles Lalueze-Fox, and came to lab to run a four-month project. Wishing you a pleasant and productive stay.

Research Interests:
Our lab deals with a host of topics in the general fields of molecular evolution and genetics. Among the topics that are currently pursued are:
  • Human evolution. Recent advances in ancient DNA sequencing yielded genomes (either shotgun sequences with varying degrees of coverage, or SNP arrays) of many ancient anatomically modern humans, as well as of Neanderthals and Denisovans. This open unique opportunities to study the genetic aspects of the very recent lag of our own evolution.
  • Paleo-epigenetics. We developed a technique to reconstruct full DNA methylation maps from high-coverage ancient genomes, and use it to study evolutionary changes in gene regulation, ancient environments and phenotypic adaptations.
  • Paleo-genetics. We study the genetic structure of ancient populations in Israel.
  • RNA biology. We are studying many aspects of RNA biology, including splicing, nonsense-mediated decay, 3'-end processing, and circular RNAs.
  • Multivariate data analysis. My lab is also active in some fields of applied mathematics: multivariate analysis, statistical pattern recognition, data visualization, and machine learning.
Our Web Servers
Movie Gene ORGANizer connects genes to the body parts where their phenotype is observed. Given a list of genes, Gene ORGANizer finds body parts in which these genes are enriched or depleted.

Gokhman D, Kelman G, Amartely A, Gershon G, Tsur S, Carmel L (2017). Gene ORGANizer: Linking Genes to the Organs They Affect. Nucleic Acids Research 45(W1) (Web server issue):W138-W145.

Movie JuncDB is a gene exon-intron architecture comparative database, covering nearly 40,000 sets of orthologous transcripts across 88 eukaryotic species.

Chorev M, Guy L, Carmel L (2016). JuncDB: an exon-exon junction database. Nucleic Acids Research 44(D1) (Database issue):D101-D109.

A quick summary of our research on archaic gene regulation. A narration accompanied by whiteboard animation.

A popular talk at the Israel Academy of Sciences.

Interview Liran was interviewed in the "Three who Know" radio show on the attempt to de-extinct mammoths (in Hebrew, broadcast on Apr-8th-2019).

Interview Liran was interviewed in the "Three who Know" radio show on the Neanderthalized mini-brains project declared by Svante Paabo (in Hebrew).

Interview Yoav Mathov was interviewed in Makademia.

MovieLiran was interviewed at London et Kirshenbaum about Otzi's helicobacter. Minutes 29:42 to 34:33.

Contact Information:
Room 2-342
Department of Genetics, The Alexander Silberman Institute of Life Sciences, Faculty of Science,
the Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem 91904, Israel
telephone +972 (2) 658-5103
fax +972 (2) 658-4856
email liran.carmel @
The Hebrew University
Useful links: for more details and full list